Ibuprofen intake could be leading to male infertility

Ibuprofen intake could be leading to male infertility

To investigate how the medication might impact fertility in adult males, a group of European researchers conducted a small, 6-week experiment involving 31 male subjects, ages 18-to-35.

Ibuprofen appears to affect the pituitary gland that's involved in production of the male hormone testosterone, as well as other processes linked to sperm production.

"I$3 t is also of concern that men with compensated hypogonadism may eventually progress to overt primary hypogonadism, which is characterised by low-circulating testosterone and prevalent symptoms including reduced libido, reduced muscle mass and strength, and depressed mood and fatigue", the team writes.

On a positive note, the disorder remains totally reversible when the ibuprofen is taken over a brief period, Bernard Jégou, a co-author at French National Institute of Health and Medical Research, told CNN.

To avoid these side-effects, doctors caution against taking Ibuprofen for more longer than ten days in a row, per the FDA's warning. However, it's not at all clear that the consequences of prolonged ibuprofen use would be reversible.

One of the most commonly used drugs to get relief from pain is ibuprofen. The infertility factor is a direct result of an unchecked change in male hormones.

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But the amount and frequency of ibuprofen use in the study is fairly atypical-the maximum recommended dosage of 1,200 milligrams per day every day for two weeks.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat fever, pain, and inflammation.

Scientists warn that ibuprofen could be wrecking men's fertility by making their balls shrivel up.

Dr Richard Quinton, Senior Lecturer in Endocrinology at Newcastle University, and member of the Society for Endocrinology, said: 'In women pregnant with male foetuses, there are already data suggesting a potential long term effect on testicular function of the offspring of regular paracetamol taken during pregnancy.

"People taking over-the-counter ibuprofen should not be concerned by this research".

John Smith, chief executive of the Proprietary Association of Great Britain, the United Kingdom trade association representing manufacturers of branded over-the-counter medicines, said: "The researchers highlight that further studies would be required to determine the possible effect ibuprofen could have on human reproductive and physical disorders, specifically in men". No direct effect on fertility was shown, but the results of this initial study suggest that it warrants further investigation.

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